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Thank you for the detailed write-up and for already checking permissions, cache, and VPN I understand how disruptive it is to be blocked from creating eDiscovery cases. The good news is that AxiosError: Network Error is a client-side network/reachability issue (the browser's request to the Purview API isn't getting through), rather than a permissions problem which matches what your admin found.
Please try these in order:
- Isolate the browser/profile
- Open an InPrivate/Incognito window, disable all extensions, and retry creating the eDiscovery case.
- Test a different browser and, if possible, a different machine on the same network.
- Isolate the network/VPN
- Disconnect VPN, wait ~1 minute, reconnect, and retry.
- Test from a different network (e.g., mobile hotspot, no VPN). If it works off-VPN but fails on corporate network, the block is in your corporate proxy/firewall engage your network team.
- Validate firewall/proxy & TLS (network team)
- Allow outbound HTTPS/443 to the required Microsoft endpoints, including the M365/Defender/Purview portal URLs (e.g.,
login.microsoftonline.com,*.security.microsoft.com,security.microsoft.com,*.blob.core.windows.net,secure.aadcdn.microsoftonline-p.com)2. - Confirm TLS 1.2 is enabled and that SSL/TLS inspection is not breaking the connection to Microsoft services.
- Confirm your Purview/compliance setup does not have Public network access = Deny / private endpoint that would require access from inside the corporate VNet2.
- If still failing
- Capture a browser network trace (HAR) while reproducing the error, and open a Microsoft support case with the trace attached so we can pinpoint the exact blocked endpoint.
Reference docs: Troubleshoot portal access / required URLs and Resolve eDiscovery errors.
Please run steps 1–2 first and let me know the results ,that will tell us whether the block is browser-side or network-side.